Jacqueline was married to Clarence Bouvier, now deceased. While she may also have a generally negative opinion of Homer like Patty and Selma, this seemed to soften over the years she even states 'Patty and Selma are a sort of evil' when they purposely provoked Homer one night. She has, in common with Patty and Selma, a pessimistic and critical outlook on life, rarely smiling.

She began smoking when Homer and Marge got together but has since quit. When Marge was a little girl, Jacqueline had a blue beehive hairdo like Marge's, and her voice was also very similar to Marge's as an adult. Jacqueline shares many Bouvier family traits with her daughters.